CAPTURING THE DIFFERENCES BETWEEN HUMORAL IMMUNITY IN THE NORMAL AND TUMOR ENVIRONMENTS FROM REPERTOIRE-SEQ OF B-CELL RECEPTORS USING SUPERVISED MACHINE LEARNING

Capturing the differences between humoral immunity in the normal and tumor environments from repertoire-seq of B-cell receptors using supervised machine learning

Abstract Background The recent success of immunotherapy in treating tumors has attracted increasing interest in research related to the adaptive immune system in the tumor microenvironment.Recent advances in next-generation sequencing technology enabled the sequencing of whole T-cell receptors (TCRs) and B-cell receptors (BCRs)/immunoglobulins (Igs

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Unrelated Parallel Machine Scheduling with Sequence-Dependent Setup Times in Multi-Factory Production Network: Modeling and Algorithm

Today, due to some challenges and competition, such as external pressures, factories are forced to reduce production time, traditional centralized production scheduling is not flexible enough to respond to rapid market changes.In such an environment, factories decide to merge and Mastectomy Care form a multi-factory production network to work more

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Rice microtubule-associated protein OsMAP65-3.1, but not OsMAP65-3.2, plays a critical role in phragmoplast microtubule organization in cytokinesis

In plants, MAP65 preferentially cross-links the anti-parallel microtubules (MTs) and plays an important role for cytokinesis.However, the functions of MAP65 isoforms in rice (Oryza sativa.L) are largely unknown.Here, we identified two MAP65-3 homologs in rice, OsMAP65-3.1 and OsMAP65-3.2.We found that both OsMAP65-3.1 and OsMAP65-3.2 were similar i

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Prospects of blockchain application in smart agriculture

At present time,China is entering an important period of upgradation and transitionin agriculture,therefore,promoting smart agriculture development will be becoming the prior way with integration of modern information technology.Firstly,the current status of agriculture in China and the necessity Zodiac Nature2 Fusion Soft Parts of smart agricultur

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In vitro and in vivo evaluation of biologically synthesized silver nanoparticles for topical applications: effect of surface coating and loading into hydrogels

Aml I Mekkawy,1 Mohamed A El-Mokhtar,2 Nivien A Nafady,3 Naeima Yousef,3 Mostafa A Hamad,4 Sohair M El-Shanawany,5 Ehsan H Ibrahim,5 Mahmoud Elsabahy5–8 1Department of Pharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, Sohag University, Sohag, 2Department of Microbiology and Immunology, Faculty of Medicine, 3Department of Botany and Mi

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